Kudzu vine extract for alcohol treatment Non 12 Step Drug Rehab and Alcohol Treatment

• pragati
• December 31, 2021
• Sober living
• 0 Comments

McLean Hospital has licensed the production of kudzu extract (NPI-031) to Natural Pharmacia International , Inc. that markets it as Alkontrol-Herbal™. Overconsumption of alcohol has significant negative effects on an individual’s health and https://ecosoberhouse.com/ contributes to an enormous economic impact on society as a whole. Pharmacotherapies to curb excessive drinking are important for treating alcohol use disorders. Kudzu has traditionally served as a remedy for diarrhea for over 2,000 years.

In addition to digestion, these receptors promote absorption of nutrients, blood sugar homeostasis, and can even help with weight control. Moreover, specific bitter receptors seem to promote the elimination of absorbed toxins from the gut [22-24]. The researchers next plan to use Magnetic Resonance Imaging to examine the effects of kudzu on how quickly alcohol gets into the brain.

Kudzu Root Helps Conquer Alcohol Craving

This is the first ever pilot results showing that the complex Declinol, significantly reduced Alcohol Use Disorders Identification Test scores in moderate to heavy drinkers in a naturalistic setting (Figure 1 and 2; Table 3). While this is a small pilot study requiring additional large scale controlled studies, we are encouraged. To our kudzu for alcohol cravings knowledge the present pilot is the first such a study in the world that has systematically evaluated this novel complex in humans. Falcatum, administered orally to rats at a daily dose of 500 mg/kg for 3 days, normalized liver functions as determined by serum alkaline phosphatase levels in rats treated with carbon tetrachloride .

• As a safe, over-the-counter preparation, kudzu may be used alone in initial attempts to curb alcohol consumption, but it may also become a useful adjunct to the currently available prescription medications.
• Recent research suggests that kudzu root extract may, in fact, be able to relieve alcohol cravings.
• Keung, not directly involved in Lukas’ study, said he has extracted a compound from kudzu root that he hopes to turn into a drug for reducing alcoholics’ cravings.
• It used to be assumed that bitters only stimulated receptors in the mouth, and then somewhat in the digestive tract.
• However, limited clinical studies exist to recommend use for any indication.

Puerarin suppressed the addictionmediated abnormalities but did not affect the inflammation-related abnormalities. In a laboratory experimental setting, subjects will be treated with placebo or 2 grams of kudzu extract 2.5 hours before an afternoon drinking session. The investigators hypothesis is that the kudzu pretreatment will reduce alcohol consumption in this free choice, self-administration paradigm.

Potential downsides

Bohn MJ, Krahn DD, Staehler BA. Development and initial validation of a measure of drinking urges in abstinent alcoholics. When taking kudzu, you may experience side effects such as itchiness/skin irritation, dizziness or upset stomach. If you’ve recently had surgery, you also shouldn’t take kudzu. Kudzu was first brought to the United States from Japan in the late 19th century at the 1876 World’s Fair. Those in attendance took a liking to the plant for its beauty and long vines.

These problems may have to be addressed in future studies and may require additional therapies and neurochemical epigenetic modifications. Chai hu , one of the most frequently used herbs in Chinese herbal medicine, has positive benefits in cases of liver toxicity especially due to alcoholism , analgesic properties as well as sedative activity . Ashwagandha is sometimes used for alcohol withdrawal and cravings.

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Our laboratory has been involved in assessing an extract of the kudzu root for its ability to reduce alcohol consumption in humans. In the first, kudzu extract was administered for 7 days and acute binge drinking was suppressed (Lukas et al., 2005). In the second, participants who were treated for 4 weeks with kudzu extract significantly reduced their alcohol consumption during weeks 2 through 4 of the study (Lukas et al., 2013).